| 07 Août 2016
The company’s latest report*  states that this steady growth, which will occur across the seven major  markets of the US, France, Germany, Italy, Spain, the UK, and Japan,  will be driven primarily by the rise in sales surrounding the VTE  primary prophylaxis space, which is projected to increase from $2.4  billion in 2015 to $3.5 billion by 2025, at a CAGR of 4.01%. Michela McMullan, Ph.D., GlobalData’s Analyst covering Cardiovascular  and Metabolic Disorders, explains: “Novel oral anticoagulants (NOACs),  which are used to prevent and treat VTE, will primarily drive the  market, and represent important advances over warfarin, a cheap and  established anticoagulant. “This is because NOACs do not require routine blood monitoring or  dose adjustments, have fewer drug-drug interactions, do not produce  major dietary effects, and in terms of efficacy and safety, have been  proven to be non-inferior, if not superior, compared with warfarin.” GlobalData believes that as  physician familiarity with these drugs increases, and experience is  gained in selecting the appropriate NOAC dependent on a patient’s risk  profile, further NOAC uptake will occur across all markets. Indeed,  Pradaxa, Xarelto, and Eliquis, which are all currently available, will  see improved uptake over the forecast period. In addition, the recent  launch of a fourth NOAC, Savaysa, in the US and Japan will give  physicians further treatment options when deciding on which  anticoagulant is most suitable for their patients, and is also expected  to impact overall NOAC uptake. McMullan continues: “Despite  the benefits that NOACs will bring to the VTE market, the treatment  space still requires a transformational therapy to push its growth rate  up beyond current levels. In order to develop a drug that offers  transformational changes in terms of safety instead of incremental  benefits, focus would need to be turned towards better renal function  and optimal care for cancer patients. “A drug with a superior renal  clearance profile could command premium pricing in this market and would  be accepted more easily. The ideal drug should be oral, have a  once-a-day dosing, should not depend on monitoring, and should be usable  for patients in all stages of renal impairment.” *PharmaPoint: Venous Thromboembolism – Global Drug Forecast and Market Analysis to 2025 -ENDS-
LONDON,  UK (GlobalData), 1 August 2016 - The therapeutics market for venous  thromboembolism (VTE), a condition which comprises deep vein thrombosis  and pulmonary embolism, is set to rise from $2.8 billion in 2015 to $3.7  billion by 2025, representing a Compound Annual Growth Rate (CAGR) of  2.89%, according to research and consulting firm GlobalData.









