| 29 Octobre 2016
London – 27 October 2016 - The seasonal influenza  vaccine market across the seven major markets (7MM) of the US, France,  Germany, Italy, Spain, the UK, and Japan, will rise from $3.1 billion in  2015 to $4.3 billion by 2025, at a compound annual growth rate of 3.3%,  according to research and consulting firm GlobalData.
 The company’s latest report states that the main growth drivers during the forecast period will  include amendments to the national immunization schedules of the US and  the UK, the expansion of egg-based quadrivalent seasonal influenza  vaccines across Germany, Italy, France, and Spain, and the transition  from egg-based to cell culture-based vaccines. Christopher J. Pace,  Ph.D., GlobalData’s Director of Infectious Diseases, explains: “For the  past few decades, children have not been the focus of season influenza  immunization recommendations in developed nations. “More recently, developed  countries such as the US and the UK have issued expanded recommendations  for the vaccination of healthy children and adolescents against  seasonal influenza, thereby indirectly protecting high-risk groups such  as the elderly and the immunocompromised from disease by disrupting  community transmission. This generates a significant new opportunity for  market penetration.” Quadrivalent influenza vaccines, which contain antigens against two  influenza type A and two influenza type B subtypes, offer broader  coverage than trivalent (two influenza A and a single influenza B  strain) formulations. In 2015, Japan replaced its trivalent, seasonal  influenza vaccines with quadrivalent formulations, and it is expected  that trivalent vaccines will be virtually absent from the US market  within the next five years. Quadrivalent vaccines will also expand  throughout Europe by 2025. Pace continues: “Although  the vaccination rate across the 7MM is anticipated to remain stable  during the next decade, the higher price commanded by quadrivalent  vaccines and other next-generation immunizations, such as Sanofi’s  Fluzone High-Dose and CSL Limited’s Fluad, is expected to drive market growth. “In regards to the  transition from egg-based to cell culture-based vaccines, 2016 saw CSL  Limited launch the first quadrivalent cell culture-based vaccine on the  US market indicated for the immunization of children over four years old  – Flucelvax. Its novel manufacturing processes decrease production time  compared to egg-based vaccine development and also can be administered  to individuals who have egg allergies, giving cell culture-based  vaccines an important edge in an intensely competitive marketplace. “Novavax’s and Mitsubishi  Tanabe’s novel virus-like particle vaccines are also anticipated to  further revitalize an influenza market that is gradually moving towards  the eventual development of a universal seasonal influenza vaccine.”